Copyright 2002 David A. Wheeler, Ph.D., PHR, CMT NoStress@mail.com   Last updated 10/11/05 04:09 PM

Ecstasy This material was taken from: (Holland, M.D>, Julie, Ed. 2001, Ecstasy: The complete guide. Park Street Press. www.InnerTraditions.com). x

Chemical Name: MDMA (methylenedioxymethamphetamine)

Street Name: Ecstasy, Adam, X, XTC, E, Rolls

Category of Drug: empathogen (not hallucinogen)

Natural Source: Safrole is the precursor in the synthesis of MDMA.

Safrole is found in sassafras root and Myristica fragrans the tree that gives nutmeg and mace

Similar substances are found in parsley, dill and the calamus root (Shulgin, A and A. Shulgin, 1991. PIHCAL: A cemical love storey. Berkeley: Transform Press)

Common contaminants:- can lead to serotonin syndrome when mixed with Ecstasy:  DXM (dextromethorphan), speet, Eve.  (www.DanceSafe.org)

Similar Drugs: methamphetamine (speed), MDA (3,4-methylenedioxyamphetamine) , MDE (Eve) (methylenedioxyethylamphetamine), mescaline

Neurological effects: Increase release of 5-HT (serotonin), dopamine, and ADH (vasopressin)

Psychological effect: increased empathy and sense of well being. "hug drug" but decreases ability to have an erection or orgasm.

Tolerance: after first few uses appeal decreases (already learned how to be empathic and not worth the side effects). (p. 27)

Withdrawal: depression 2 -5 days after even one use

Dosage: 125 mg (p. 55)

Danger of overdose: Serotonin syndrome (fatal 10 - 15% of time) especially likely if used in conjunction with other serotonin enhancing drugs such as antidepressants. Hyperthermia (fever).

DEA Schedule I: Physicians not able to prescribe



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